The following includes selected scientific publications regarding AuroLase® Therapy and other commercial applications of AuroShell® Particles (also known as nanoshells).

AuroLase Therapy for the PhotoThermal Ablation of Tumors

"Selective Nanoparticle-directed Ablation of the Canine Prostate."
Schwartz, J.A., Price, R.E., Gill-Sharp, K.L., Sang, K.L., Khorchani, J., Goodwin, B.S., .L., Payne, J.D.
Laser Surg Med. 2011 Mar; 43(3):213-20. doi: 10.1002/lsm.21039.

"Feasibility Study of Particle-Assisted Laser Ablation of Brain Tumors in an Orthotopic Canine Model."
Schwartz, J.A., Shetty, A.M., Price, R.E., Stafford, R.J., Wang, J.C., Uthamanthil, R.K., Pham, K., McNichols, R.J., Coleman, C.L., Payne, J.D.
Cancer Res 2009 Feb 15; 69:(4), 1659-1667.

"Selective Prostate Cancer Thermal Ablation with Laser Activated Gold Nanoshells."
Stern, J. M., Stanfield, J., Kabbani, W., Hsieh, J., Cadeddu, J.A.
The Journal of Urology. Vol. 179, 748-753, February 2008.

"Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles."
O'Neal, D.P., Hirsch, L.R., Halas, N.J., Payne, J.D., West, J.L.
Cancer Letters. 2004 Jun 25; 209(2):171-176.

"Nanoshell-assisted tumor ablation using near infrared light under magnetic resonance guidance."
Hirsch, L.R., Stafford, R.J., Sershen, S.R., Halas, N.J., Hazle, J.D., West, J.L.
Proc. Natl. Acad. Sci. USA, 100 (2003): 113549-113554.

"Nanoshell-mediated photothermal therapy improves survival in a murine glioma model."
Day, E.S., Thompson, P.A., Zhang, L., Lewinski, N.A., Ahmed, N., Drezek, R.A., Blaney, S.M., West, J.L.
J. Neurooncol., 2010 Nov 26 [Epub ahead of print].

AuroLase Therapy as an Adjunct to Radiation Therapy or Imaging

"Integrin avß3-targeted Gold Nanoshells Augment Tumor Vasculature-specific Imaging and Therapy."
Xie H., Diagaradjane P., Deorukhkar A.A., Goins B., Bao A., Phillips W.T., Wang Z., Schwartz J., Krishnan S.
Int J Nanomedicine. 2011;6:259-69. Epub 2011 Jan 27.

"Intra-organ Biodistribution of Gold Nanoparticles Using Intrinsic Two-photon Induced Photoluminescence."
Park J., Estrada A., Schwartz J.A., Diagaradjane P., Krishnan S., Dunn A.K., Tunnell J.W. Lasers Surg Med. 2010 Sep; 42(7):630-639.

"Photothermal Therapy in a Murine Colon Cancer Model using Near-infrared Absorbing Gold Nanorods."
Goodrich G.P., Bao L., Gill-Sharp K.L., Wang J., Payne J.D.
J Biomed Opt. 2010 Jan-Feb; 15(1):018001.

"Near-infrared Narrow-band Imaging of Gold/Silica Nanoshells in Tumors."
Puvanakrishan P., Park J., Diagaradjane P., Schwartx J.A., Coleman C.L., Gill-Sharp K.L., Sang K.L., Payne J.D., Krishnan S., Tunnell J.W.
J Biomed Opt. 2009 Mar-Apr; 14(2):024044.

Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy."
Diagaradjane P., Shetty A., Wang J.C., Elliott A.M., Schwartz J., Shentu S., Park H.C., Deorukhkar A., Stafford R.J., Cho S.H., Tunnell J.W., Hazle J.D., Krishnan S.
Nano Lett. 2008 May;8(5):1492-1500.

"Photothermal Detection of Gold Nanoparticles Using Phase-sensitive Optical Coherence Tomography."
Adler D.C., Huang S.W., Huber R., Fujimoto J.G.
Opt Express. 2008 Mar 31;16(7):4376-4393.

"Two-photon-induced Photoluminescence Imaging of Tumors Using Near-infrared Excited Gold Nanoshells."
Park J., Estrada A., Sharp K., Sang K., Schwartz J.A., Smith D.K., Coleman C., Payne J.D., Korgel B.A., Dunn A.K, Tunnell J.W.
Opt Express. 2008 Feb 4;16(3):1590-1599.

"Near-infrared Resonant Nanoshells for Combined Optical Imaging and Photothermal Cancer Therapy."
Gobin A.M., Lee M.H., Halas N.J., James W.D., Drezek R.A., West J.L.
Nano Lett. 2007 Jul;7(7):1929-1934.

Other Commercial Applications

"Three-wavelength Murine Photoplethysmography for Estimation of Vascular Gold Nanorod Concentration."
Michalak G.J., Schwartz J.A., Goodrich G.P., O'Neal D.P.
Opt Express. 2010 Dec 6; 18(25):26535-49. doi: 10.1364/OE.18.026535.

"In-vivo Photoacoustic Microscopy of Nanoshell Extravasation from Solid Tumor Vasculature."
Li M.L., Wang J.C., Schwartz J.A., Gill-Sharp K.L., Stoica G., Wang L.V.
J Biomed Opt. 2009 Jan-Feb; 14(1):010507.

"Surface-enhanced Raman scattering on tunable plasmonic nanoparticle substrates."
Jackson, J.B. and Halas, N.J.
Proc. Natl. Acad. Sci. USA 101, 17930-17935 (2004).

"Temperature-sensitive hydrogels with SiO2–Au nanoshells for controlled drug delivery."
Bikram M., Gobin A.M.,Whitmire R.E. and West J.L. 
Journal of Controlled Release, Volume 123, Issue 3, 20 November 2007, 219-227.

"Optically controlled valves for microfluidics devices."
Sershen, S.R., Ng, M.A., Halas, N.J., Beebe, D., West, J.L.
Advanced Materials, 17 (2005): 1366-1368.